SCHEMBL28535787

SCHEMBL28535787

NC(=O)CNC(=O)[C@H](Cc1ccc2ccccc2c1)OC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.44
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
NLN Q9BYT8 1/20 0.42
OPRD1 P41143 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
MC5R P33032 2/20 0.41
MC1R Q01726 2/20 0.41
FCER2 P06734 2/20 0.41
CTSB P07858 2/20 0.40
CTSS P25774 2/20 0.40
MMP9 P14780 2/20 0.40
CTSL P07711 1/20 0.40
CTSK P43235 1/20 0.40
MMP13 P45452 1/20 0.40
ADAM17 P78536 1/20 0.40
FAAH O00519 1/20 0.40
MME P08473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8482123 0.86 FCER2 (0.51) MMP1PPARGPPARANLNMC5R
SCHEMBL7276239 0.78 PPARG (0.45) MMP1PPARGPPARAHTR2AHTR2C
SCHEMBL7276245 0.78 PPARG (0.45) MMP1PPARGPPARAHTR2AHTR2C
SCHEMBL26605072 0.78 OPRD1 (0.56) NLNOPRD1HTR2AHTR2CHTR2B
SCHEMBL26605069 0.78 OPRD1 (0.56) NLNOPRD1HTR2AHTR2CHTR2B
SCHEMBL26605067 0.77 OPRD1 (0.53) OPRD1FCER2CTSBCTSSMMP9
SCHEMBL26605062 0.77 OPRD1 (0.53) OPRD1FCER2CTSBCTSSMMP9
SCHEMBL7274085 0.74 PPARG (0.41) MMP1PPARGPPARAHTR2AHTR2C
SCHEMBL7274093 0.74 PPARG (0.41) MMP1PPARGPPARAHTR2AHTR2C
SCHEMBL30104067 0.71 OPRD1 (0.54) NLNOPRD1HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113150068-B Peptide compound, application thereof and composition containing peptide compound 尚华医药科技(江西)有限公司 2023-04-04 CN disclosed
CN-113150068-A Peptide compound, application thereof and composition containing peptide compound 尚华医药科技(江西)有限公司 2021-07-23 CN disclosed
CN-109517039-B Peptide compound, application thereof and composition containing peptide compound 尚华医药科技(江西)有限公司 2021-03-19 CN disclosed