SCHEMBL28536004

SCHEMBL28536004

FC(F)(F)c1ccc(CC[SiH](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.48
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
KIF11 P52732 1/20 0.44
MAOB P27338 1/20 0.43
PDPK1 O15530 1/20 0.43
PLAAT3 P53816 1/20 0.42
PLAAT5 Q96KN8 1/20 0.42
PLAAT2 Q9NWW9 1/20 0.42
PLAAT4 Q9UL19 1/20 0.42
MIF P14174 1/20 0.41
MAPT P10636 1/20 0.41
SRD5A2 P31213 1/20 0.39
IDO1 P14902 1/20 0.39
LTA4H P09960 1/20 0.39
EPHX2 P34913 1/20 0.39
ALOX15B O15296 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TRPV6 Q9H1D0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25909613 0.82 ESRRG (0.46) EPHX2
SCHEMBL25909608 0.80 ALDH1A1 (0.46) TAAR1ALDH1A1TSHRMAOBIDO1
SCHEMBL25909619 0.79 TAAR1 (0.43) TAAR1ALDH1A1MAOBPLAAT3PLAAT5
SCHEMBL4811927 0.78 TAAR1 (0.61) TAAR1ALDH1A1TSHRKIF11MAOB
SCHEMBL25909610 0.77 FFAR1 (0.47) TAAR1ALDH1A1TSHRIDO1
SCHEMBL25909624 0.76 TAAR1 (0.43) TAAR1TSHRMAOBPDPK1PLAAT3
SCHEMBL25909607 0.76 CYP1A2 (0.43) TAAR1TSHRPLAAT3PLAAT5PLAAT2
SCHEMBL28533680 0.76 TAAR1 (0.43) TAAR1ALDH1A1PDPK1PLAAT3PLAAT5
SCHEMBL2301117 0.75 TAAR1 (0.57) TAAR1ALDH1A1TSHRKIF11MAOB
SCHEMBL934227 0.73 TAAR1 (0.73) TAAR1ALDH1A1TSHRMAOBMIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112387313-B Tridentate phenanthroline manganese catalyst and application thereof in synthesis of organic silicon/boron compound 中山大学 2022-08-16 CN disclosed
CN-112387313-A Tridentate phenanthroline manganese catalyst and application thereof in synthesis of organic silicon/boron compound 中山大学 2021-02-23 CN disclosed