SCHEMBL25909613

SCHEMBL25909613

CC(C)(C)c1ccc(CC[SiH](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESRRG P62508 2/20 0.46
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
KCNH2 Q12809 1/20 0.42
SLC13A5 Q86YT5 2/20 0.40
SIGMAR1 Q99720 2/20 0.38
LMNA P02545 1/20 0.38
KDM1A O60341 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGES2 Q9H7Z7 1/20 0.38
NR1H4 Q96RI1 3/20 0.37
EPHX2 P34913 2/20 0.37
GRIA4 P48058 1/20 0.37
NR4A2 P43354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28536004 0.82 TAAR1 (0.48) EPHX2
SCHEMBL25909608 0.80 ALDH1A1 (0.46) RAB9ANPC1SIGMAR1LMNAKDM1A
SCHEMBL25909607 0.79 CYP1A2 (0.43) RAB9ANPC1KCNH2LMNAPOLB
SCHEMBL6547537 0.78 RAB9A (0.56) ESRRGRAB9ANPC1KCNH2SLC13A5
SCHEMBL25909610 0.77 FFAR1 (0.47) KCNH2LMNAGAA
SCHEMBL1325663 0.77 KCNH2 (0.50) ESRRGKCNH2SLC13A5SIGMAR1LMNA
SCHEMBL28533680 0.76 TAAR1 (0.43) RAB9ASIGMAR1
SCHEMBL25909619 0.76 TAAR1 (0.43) RAB9ANPC1LMNAEPHX2
SCHEMBL25909624 0.76 TAAR1 (0.43) SIGMAR1LMNA
SCHEMBL28524211 0.75 LTA4H (0.53) RAB9ANPC1KCNH2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241597-A1 PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS TEXAS TECH UNIVERSITY SYSTEM 2023-08-03 US disclosed
CN-112387313-B Tridentate phenanthroline manganese catalyst and application thereof in synthesis of organic silicon/boron compound 中山大学 2022-08-16 CN disclosed
CN-112387313-A Tridentate phenanthroline manganese catalyst and application thereof in synthesis of organic silicon/boron compound 中山大学 2021-02-23 CN disclosed