SCHEMBL28536136

SCHEMBL28536136

O=C=Nc1ccc(CCCCCC(=O)OCc2ccc(CO)c([N+](=O)[O-])c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.41
FAAH O00519 1/20 0.41
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP4Z1 Q86W10 2/20 0.36
KMT2A Q03164 3/20 0.35
MEN1 O00255 1/20 0.35
CYP4F11 Q9HBI6 1/20 0.34
CYP4F12 Q9HCS2 1/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28910177 0.84 ALDH1A1 (0.48) MGLLFAAHALDH1A1TDP1KMT2A
SCHEMBL28910179 0.80 ALDH1A1 (0.45) MGLLFAAHALDH1A1TDP1KMT2A
SCHEMBL28530188 0.79 MGLL (0.40) MGLLFAAHALDH1A1TDP1KMT2A
SCHEMBL28546971 0.78 ALDH1A1 (0.40) MGLLFAAHALDH1A1TDP1KMT2A
SCHEMBL28538358 0.77 ALDH1A1 (0.42) ALDH1A1TDP1KMT2AMEN1MAPT
SCHEMBL28551686 0.77 TSHR (0.53) ALDH1A1TDP1KMT2AMEN1MAPT
SCHEMBL28535851 0.77 ALDH1A1 (0.41) MGLLFAAHALDH1A1TDP1KMT2A
SCHEMBL30541772 0.73 ALDH1A1 (0.39) MGLLFAAHALDH1A1TDP1KMT2A
SCHEMBL28539053 0.72 ALDH1A1 (0.37) ALDH1A1TDP1KMT2AMEN1MAPT
SCHEMBL28536856 0.70 ALDH1A1 (0.39) ALDH1A1TDP1MAPTRAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574089-B Photo-induced multifunctional crosslinking agent, preparation method and application thereof 中国科学院上海药物研究所 2023-09-05 CN disclosed
CN-112574089-A Photoinduced multifunctional cross-linking agent, and preparation method and application thereof 中国科学院上海药物研究所 2021-03-30 CN disclosed