Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.69 |
| ▸ | PRNP | P04156 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28539313 | 0.89 | PDE10A (0.53) | PDE10APRNPMAPTALDH1A1KDM4E | |
| SCHEMBL30072276 | 0.85 | PRNP (0.50) | PDE10APRNPMAPTALDH1A1L3MBTL1 | |
| SCHEMBL28853907 | 0.83 | PDE10A (0.74) | PDE10APRNPMAPTALDH1A1L3MBTL1 | |
| SCHEMBL28529940 | 0.82 | PDE10A (0.73) | PDE10AMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL2125225 | 0.82 | PDE10A (1.00) | PDE10AMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL21004738 | 0.81 | PRNP (0.50) | PDE10APRNPMAPTALDH1A1L3MBTL1 | |
| SCHEMBL16651929 | 0.81 | PRNP (0.61) | PDE10APRNPMAPTALDH1A1L3MBTL1 | |
| SCHEMBL30999690 | 0.80 | PDE10A (0.96) | PDE10AMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6858227 | 0.80 | PDE10A (0.96) | PDE10AMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL27610987 | 0.80 | PDE10A (0.96) | PDE10AMAPTALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521333-A | Synthesis method of chiral 2, 3-disubstituted tetrahydroquinoline derivative | 中国科学院大连化学物理研究所 | 2021-03-19 | — | — | CN | disclosed |