Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418012 | 0.82 | PTGS2 (0.57) | MAPTALDH1A1KMT2AMEN1PTGS2 | |
| SCHEMBL18865676 | 0.81 | PTGS2 (0.40) | MAPTALDH1A1KMT2AMEN1PTGS2 | |
| SCHEMBL13181161 | 0.81 | PTGS2 (0.40) | PTGS2 | |
| SCHEMBL1313133 | 0.80 | PDE3B (0.43) | MAPTALDH1A1PTGS2KDM4ENPC1 | |
| SCHEMBL19529676 | 0.77 | ALDH1A3 (0.53) | MAPTALDH1A1KMT2AMEN1PKM | |
| SCHEMBL28910170 | 0.74 | MAPT (0.46) | MAPTALDH1A1KMT2AMEN1PKM | |
| SCHEMBL28177689 | 0.73 | KDM4E (0.46) | ALDH1A1KMT2AMEN1PTGS2PTGS1 | |
| SCHEMBL10916369 | 0.72 | PTGS1 (0.57) | MAPTALDH1A1KMT2AMEN1PTGS2 | |
| SCHEMBL8989243 | 0.72 | PARP1 (0.44) | MAPTALDH1A1CYP2A6KMT2AMEN1 | |
| SCHEMBL5415921 | 0.71 | PTGS2 (0.53) | MAPTALDH1A1KMT2AMEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396505-A | Methods of treating inflammation | 维鲁公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-115379835-A | Methods of treating coronavirus | 维鲁公司 | 2022-11-22 | — | — | CN | disclosed |
| EP-4061349-A1 | METHODS OF TREATING CORONAVIRUS | Veru Inc. (US) | 2022-09-28 | — | — | EP | disclosed |
| CN-112512522-A | Compounds for the treatment of triple negative breast and ovarian cancer | 田纳西大学研究基金会 | 2021-03-16 | — | — | CN | disclosed |
| CN-112437664-A | Compounds for the treatment of pancreatic cancer | 田纳西大学研究基金会 | 2021-03-02 | — | — | CN | disclosed |