Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064728 | 0.83 | MAPT (0.40) | LMNAGPR119KDM4EALDH1A1MAPT | |
| SCHEMBL852448 | 0.83 | POLB (0.43) | GPR119POLB | |
| SCHEMBL30511570 | 0.79 | PARP1 (0.36) | LMNAKDM4EMAPTKMT2ATP53 | |
| SCHEMBL1836164 | 0.79 | PARP1 (0.36) | LMNAKDM4EMAPTKMT2ATP53 | |
| SCHEMBL29106412 | 0.79 | SMN1; SMN2 (0.33) | LMNAMAPTKMT2ATP53 | |
| SCHEMBL29549990 | 0.77 | SMN1; SMN2 (0.53) | LMNAALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL205655 | 0.77 | SMN1; SMN2 (0.53) | LMNAALDH1A1MAPTKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL29106429 | 0.77 | SMN1; SMN2 (0.33) | LMNAKMT2ATP53 | |
| SCHEMBL7051387 | 0.71 | SMN1; SMN2 (0.36) | LMNAHTR3ATP53HRH1CYP2C19 | |
| SCHEMBL31503999 | 0.70 | GSK3A (0.44) | LMNAKDM4EALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107205993-B | Organic compounds | 细胞内治疗公司 | 2021-03-09 | — | — | CN | claimed |
| CN-107849040-B | Tricyclic derivative compound, preparation method thereof, and pharmaceutical composition containing the same | 肿瘤学治疗公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-107205993-B | Organic compounds | 细胞内治疗公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-100441579-C | Tetrahydronaphthyridine derivatives as cholesteryl ester transfer protein inhibitors | TANABE SEIYAKU CO (JP) | 2008-12-10 | — | — | CN | disclosed |
| CN-1938301-A | Tetrahydronaphthyridine derivatives as cholesteryl ester transfer protein inhibitors | TANABE SEIYAKU CO (JP) | 2007-03-28 | — | — | CN | disclosed |