Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549990 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAP2RX4BCHEGAA | |
| SCHEMBL6110992 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAP2RX4BCHEGAA | |
| SCHEMBL411007 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAP2RX4BCHEGAA | |
| SCHEMBL29639604 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAP2RX4BCHEGAA | |
| SCHEMBL3719677 | 0.88 | BCHE (0.50) | SMN1; SMN2LMNAP2RX4BCHEMAPK1 | |
| SCHEMBL6110401 | 0.86 | P2RX4 (0.64) | SMN1; SMN2LMNAP2RX4P2RX1P2RX3 | |
| SCHEMBL27785934 | 0.84 | P2RX4 (0.58) | SMN1; SMN2LMNAP2RX4BCHEGAA | |
| SCHEMBL28802473 | 0.84 | P2RX4 (0.63) | SMN1; SMN2P2RX4GAAMAPK1P2RX1 | |
| SCHEMBL22264116 | 0.83 | P2RX4 (0.41) | SMN1; SMN2LMNAP2RX4BCHEGAA | |
| SCHEMBL8769449 | 0.82 | P2RX4 (0.43) | SMN1; SMN2LMNAP2RX4BCHEP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | claimed |
| WO-2006033004-A1 | QUINOLINE COMPOUNDS AS CETP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2006-03-30 | — | — | WO | claimed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | claimed |
| EP-1305007-A2 | PHARMACEUTICAL COMPOSITIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | Pfizer Products Inc. (US) | 2003-05-02 | — | — | EP | claimed |
| WO-2002022618-A1 | METHOD FOR PREPARING CAMPTOTHECIN AND ITS DERIVATIVES | AVENTIS PHARMA S.A. (FR) | 2002-03-21 | — | — | WO | claimed |
| WO-2002011710-A2 | PHARMACEUTICAL COMPOSITIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | PFIZER PRODUCTS INC. (US) | 2002-02-14 | — | — | WO | claimed |
| CN-119954828-A | Parallel ring compound and preparation and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-116322699-B | Parallel ring compound and preparation and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-116322699-A | Parallel ring compound and preparation and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-114591212-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-06-07 | — | — | CN | disclosed |
| WO-2022063303-A1 | A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2022-03-31 | — | — | WO | disclosed |
| WO-2021161263-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | ABBVIE INC. (US) | 2021-08-19 | — | — | WO | disclosed |
| EP-3560923-B1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-0053537-A1 | Vinyl-3 cephalosporin derivatives and their preparation | RHONE-POULENC SANTE (FR) | 1982-06-09 | — | — | EP | disclosed |
| EP-0053542-A1 | Cephalosporin derivatives, their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1982-06-09 | — | — | EP | disclosed |
| EP-0053540-A1 | Cephalosporin derivatives and their preparation | RHONE-POULENC SANTE (FR) | 1982-06-09 | — | — | EP | disclosed |
| EP-0053539-A1 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1982-06-09 | — | — | EP | disclosed |
| EP-0053072-A1 | Oxacephalosporins and their preparation | RHONE-POULENC SANTE (FR) | 1982-06-02 | — | — | EP | disclosed |
| EP-0053073-A1 | Oxacephalosporins and their preparation | RHONE-POULENC SANTE (FR) | 1982-06-02 | — | — | EP | disclosed |
| EP-0053074-A1 | Cephalosporin derivatives and their preparation | RHONE-POULENC SANTE (FR) | 1982-06-02 | — | — | EP | disclosed |