SCHEMBL28537271

SCHEMBL28537271

COc1cc(C[O])ccc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.66
ALDH1A1 P00352 2/20 0.66
GAA P10253 1/20 0.66
NFKB1 P19838 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
TAAR1 Q96RJ0 2/20 0.65
MAPK1 P28482 1/20 0.65
FOS P01100 1/20 0.62
TTR P02766 1/20 0.62
JUN P05412 1/20 0.62
NR3C1 P04150 1/20 0.62
HSD17B1 P14061 1/20 0.62
HSD17B2 P37059 1/20 0.62
LMNA P02545 1/20 0.62
GLA P06280 1/20 0.62
ALOX5 P09917 2/20 0.61
CYP3A4 P08684 2/20 0.61
PTPN1 P18031 1/20 0.61
AR P10275 1/20 0.61
PTGS1 P23219 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14373303 0.84 TAAR1 (0.65) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL29604390 0.83 PTPN1 (0.82) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL17780116 0.83 PTPN1 (0.82) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL68178 0.83 CALM1 (0.79) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL17193596 0.82 TSHR (0.73) TSHRALDH1A1GAANFKB1TDP1
Vanillyl Alcohol SCHEMBL62348 0.82 TAAR1 (0.67) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL29740697 0.82 PTPN1 (0.79) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL109504 0.82 TAAR1 (0.67) TSHRALDH1A1GAANFKB1TDP1
Vanillyl Alcohol SCHEMBL29408335 0.82 TAAR1 (0.67) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL29455076 0.82 TAAR1 (0.67) TSHRALDH1A1GAANFKB1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117412742-A Capsaicin derivatives for the treatment of idiopathic pulmonary fibrosis 艾辛全公司 2024-01-16 CN disclosed
CN-107918247-B Colored curable resin composition 住友化学株式会社 2022-03-18 CN disclosed
CN-106019840-B Colored curable resin composition 东友精细化工有限公司 2021-01-29 CN disclosed