SCHEMBL68178

SCHEMBL68178

COc1cc(Cc2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.79
TAAR1 Q96RJ0 2/20 0.69
TSHR P16473 2/20 0.69
MAPK1 P28482 1/20 0.69
FOS P01100 1/20 0.67
TTR P02766 1/20 0.67
JUN P05412 1/20 0.67
NR3C1 P04150 1/20 0.67
HSD17B1 P14061 1/20 0.67
HSD17B2 P37059 1/20 0.67
LMNA P02545 1/20 0.67
GLA P06280 1/20 0.67
CA2 P00918 1/20 0.65
ALDH1A1 P00352 3/20 0.65
CYP3A4 P08684 2/20 0.65
ALOX5 P09917 2/20 0.65
GAA P10253 1/20 0.65
NFKB1 P19838 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
PTPN1 P18031 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14243460 0.94 CALM1 (0.72) CALM1TAAR1TSHRMAPK1FOS
SCHEMBL15042812 0.92 TUBB4A (0.75) CALM1TAAR1TSHRMAPK1FOS
SCHEMBL21357334 0.92 CALM1 (0.70) CALM1TAAR1TSHRMAPK1FOS
SCHEMBL29442255 0.92 TUBB4A (0.75) CALM1TAAR1TSHRMAPK1FOS
SCHEMBL8350941 0.92 CALM1 (0.70) CALM1TAAR1TSHRMAPK1FOS
SCHEMBL28795975 0.91 CALM1 (0.68) CALM1TAAR1TSHRMAPK1FOS
SCHEMBL27758491 0.89 CALM1 (0.66) CALM1TAAR1TSHRMAPK1FOS
SCHEMBL17780116 0.87 PTPN1 (0.82) CALM1TAAR1TSHRMAPK1FOS
SCHEMBL29604390 0.87 PTPN1 (0.82) CALM1TAAR1TSHRMAPK1FOS
SCHEMBL19163980 0.86 CALM1 (0.67) CALM1TAAR1TSHRMAPK1FOS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016176194-A1 BISPHENOLS AND POLYCARBBONATES AND THE METHODS OF MAKING THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-03 WO claimed
US-20240218109-A1 LIGNIN-DERIVED AND PERFORMANCE-ENHANCED NON-ISOCYANATE POLYURETHANE THERMOSETS UNIVERSITY OF DELAWARE (US) 2024-07-04 US disclosed
US-20240218109-A1 LIGNIN-DERIVED AND PERFORMANCE-ENHANCED NON-ISOCYANATE POLYURETHANE THERMOSETS UNIVERSITY OF DELAWARE (US) 2024-07-04 US disclosed
EP-4003058-A1 NATURAL VANILLIN COMPOSITIONS RHODIA OPERATIONS (FR) 2022-06-01 EP disclosed
US-10723684-B2 Bisphenol alternative derived from renewable substituted phenolics and their industrial application UNIVERSITY OF DELAWARE (US) 2020-07-28 US disclosed
US-20170210689-A1 BISPHENOL ALTERNATIVE DERIVED FROM RENEWABLE SUBSTITUTED PHENOLICS AND THEIR INDUSTRIAL APPLICATION UNIVERSITY OF DELAWARE (US) 2017-07-27 US disclosed
US-20170210689-A1 BISPHENOL ALTERNATIVE DERIVED FROM RENEWABLE SUBSTITUTED PHENOLICS AND THEIR INDUSTRIAL APPLICATION UNIVERSITY OF DELAWARE (US) 2017-07-27 US disclosed
WO-2016176194-A1 BISPHENOLS AND POLYCARBBONATES AND THE METHODS OF MAKING THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-03 WO disclosed
US-20160299157-A1 METHODS FOR DETERMINING RELATIVE BINDING ENERGY OF MONOMERS AND METHODS OF USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-10-13 US disclosed
US-20140336259-A1 PHENOLIC COMPOUNDS WITH ANTIOXIDANT AND ANTI-CANCER PROPERTIES, ANALOGS AND SYNTHESIS THEREOF FEDERATION DES PRODUCTEURS ACERICOLES DU QUEBEC (CA) 2014-11-13 US disclosed
US-4374233-A MOLDING MATERIALS; ENGINEERING THERMOPLASTICS GENERAL ELECTRIC COMPANY (US) 1983-02-15 US disclosed
US-4368315-A AGITATED TWO-PHASE MIXTURE OF ORGANIC SOLVENT AND WATER CONTAINING STRONG BASE GENERAL ELECTRIC COMPANY (US) 1983-01-11 US disclosed
US-4360659-A Non-catalyzed interfacial polycondensation polycarbonate process GENERAL ELECTRIC COMPANY (US) 1982-11-23 US disclosed
EP-0056149-A1 Process for manufacturing aromatic polyesters KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-07-21 EP disclosed
US-4294954-A FLAME RETARDANT GENERAL ELECTRIC COMPANY (US) 1981-10-13 US disclosed
US-4281088-A Novel halobisphenolethylene polycarbonate-polyester blends GENERAL ELECTRIC COMPANY (US) 1981-07-28 US disclosed
US-4247662-A Novel halobisphenolethylene polycarbonate-vinyl aromatic resin blends GENERAL ELECTRIC COMPANY (US) 1981-01-27 US disclosed
US-4225687-A MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1980-09-30 US disclosed
US-4217438-A Polycarbonate transesterification process GENERAL ELECTRIC COMPANY (US) 1980-08-12 US disclosed
US-4118370-A ESTERIFIED HINDERED PHENOL; MOLDING MATERIALS, FIBERS, LAMINATES GENERAL ELECTRIC COMPANY (US) 1978-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210689-A1 BISPHENOL ALTERNATIVE DERIVED FROM RENEWABLE SUBSTITUTED PHENOLICS AND THEIR INDUSTRIAL APPLICATION RBBP4, GRHPR, RBBP5 CALM1 4508/4885TAAR1 2034/4885TSHR 840/4885
US-10723684-B2 Bisphenol alternative derived from renewable substituted phenolics and their industrial application GRHPR, CBR3, RBBP4 CALM1 4422/4885TAAR1 2262/4885TSHR 1169/4885
US-20140336259-A1 PHENOLIC COMPOUNDS WITH ANTIOXIDANT AND ANTI-CANCER PROPERTIES, ANALOGS AND SYNTHESIS THEREOF GPX1, CAT, GPX4 CALM1 452/4885TAAR1 3959/4885TSHR 4874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.