SCHEMBL28537661

SCHEMBL28537661

CC(C)(C)[Si](C)(C)O[C@@H]1CC(=O)N(CCO)C1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.33
FPR1 P21462 1/20 0.31
PPM1D O15297 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21389421 1.00 BRD4 (0.33) BRD4FPR1PPM1D
SCHEMBL26744875 1.00 BRD4 (0.33) BRD4FPR1PPM1D
SCHEMBL21389115 0.86 PLA2G7 (0.30)
SCHEMBL28536009 0.86 PLA2G7 (0.30)
SCHEMBL28529851 0.86 PLA2G7 (0.30)
SCHEMBL30752652 0.84 PPM1D (0.32) PPM1D
SCHEMBL35210460 0.84 PPM1D (0.32) PPM1D
SCHEMBL28532943 0.82 APEX1 (0.35) PPM1D
SCHEMBL28522829 0.82 APEX1 (0.35) PPM1D
SCHEMBL28522830 0.82 APEX1 (0.35) PPM1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112236161-A Modulators of G protein-coupled receptors 卡莫特治疗学股份有限公司 2021-01-15 CN disclosed