Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 19/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533605 | 0.83 | MAP3K5 (0.42) | MAP3K5GRM5GRM1 | |
| SCHEMBL28648131 | 0.79 | MAP3K5 (0.44) | MAP3K5 | |
| SCHEMBL28660344 | 0.78 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL28652009 | 0.77 | MAP3K5 (0.43) | MAP3K5GRM5GRM1 | |
| SCHEMBL233897 | 0.76 | MAP3K5 (0.44) | MAP3K5 | |
| SCHEMBL28649130 | 0.76 | GRM5 (0.45) | MAP3K5GRM5GRM1 | |
| SCHEMBL234409 | 0.76 | MAP3K5 (0.43) | MAP3K5GRM5GRM1 | |
| SCHEMBL28653523 | 0.75 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL28663394 | 0.75 | MAP3K5 (0.46) | MAP3K5GRM5GRM1 | |
| SCHEMBL28648560 | 0.75 | GRM5 (0.44) | MAP3K5GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071498-B | Kinase inhibitor and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-03-30 | — | — | CN | disclosed |