Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541572 | 0.87 | ALDH1A1 (0.41) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL6035964 | 0.80 | PRMT5 (0.41) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL7797897 | 0.77 | PRMT5 (0.43) | POLBALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL181071 | 0.76 | FOLH1 (0.37) | FOLH1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL29113840 | 0.73 | ALDH1A1 (0.44) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28544775 | 0.73 | CXCR4 (0.44) | HDAC1HDAC3HDAC2HDAC8ALDH1A1 | |
| SCHEMBL28538341 | 0.71 | KMT2A (0.39) | ALDH1A1MAPTMAPK1HTTTDP1 | |
| SCHEMBL28536095 | 0.71 | NPC1 (0.38) | HDAC1POLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28530175 | 0.71 | NPC1 (0.40) | POLBALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL2633079 | 0.70 | SMN1; SMN2 (0.36) | POLBALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574089-A | Photoinduced multifunctional cross-linking agent, and preparation method and application thereof | 中国科学院上海药物研究所 | 2021-03-30 | — | — | CN | disclosed |