Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610505 | 0.89 | TSHR (0.41) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL1345313 | 0.78 | — | — | |
| SCHEMBL2240752 | 0.75 | — | — | |
| SCHEMBL9396142 | 0.74 | — | — | |
| SCHEMBL5015684 | 0.72 | — | — | |
| SCHEMBL14463487 | 0.71 | — | — | |
| SCHEMBL295730 | 0.71 | TSHR (0.77) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL23210 | 0.71 | TSHR (0.77) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL651261 | 0.71 | TSHR (0.77) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL10937926 | 0.71 | TSHR (0.77) | TSHRMAPK1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597497-B2 | Gels | AORTECH INTERNATIONAL PLC (GB) | 2020-03-24 | — | — | US | disclosed |
| US-20190071543-A1 | GELS | AORTECH BIOMATERIALS PTY LTD (AU) | 2019-03-07 | — | — | US | disclosed |
| US-10059807-B2 | Gels | AORTECH INTERNATIONAL PLC (GB) | 2018-08-28 | — | — | US | disclosed |
| US-9765191-B2 | Gels | AORTECH INTERNATIONAL PLC (GB) | 2017-09-19 | — | — | US | disclosed |
| US-20170121464-A1 | GELS | AORTECH BIOMATERIALS PTY LTD. (AU) | 2017-05-04 | — | — | US | disclosed |
| US-20170114187-A9 | GELS | AORTECH INTERNATIONAL PLC (GB) | 2017-04-27 | — | — | US | disclosed |
| US-20140323676-A1 | GELS | AORTECH INTERNATIONAL PLC (GB) | 2014-10-30 | — | — | US | disclosed |
| US-8623986-B2 | Gels | Aertech International plc (GB) | 2014-01-07 | — | — | US | disclosed |
| EP-2007826-B1 | GELS | AORTECH INT PLC (GB) | 2013-12-11 | — | — | EP | disclosed |
| US-20100029802-A1 | Gels | AORTECH INTERNATIONAL PLC (GB) | 2010-02-04 | — | — | US | disclosed |
| EP-2007826-A4 | GELS | AORTECH BIOMATERIALS PTY LTD (AU) | 2009-07-01 | — | — | EP | disclosed |
| EP-2007826-A1 | GELS | AorTech Biomaterials Pty Ltd (AU) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007121513-A1 | GELS | AORTECH BIOMATERIALS PTY LTD (AU) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190071543-A1 | GELS | CAD, BRCA1, PUF60 | TSHR 2539/4885MAPK1 2220/4885MEN1 641/4885 |
| US-10597497-B2 | Gels | CAD, BRCA1, PUF60 | TSHR 2539/4885MAPK1 2220/4885MEN1 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.