Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30043363 | 0.74 | NLRP3 (0.35) | LNPEPALDH1A1HPGDATMKDM4E | |
| SCHEMBL21625485 | 0.74 | NLRP3 (0.35) | LNPEPALDH1A1HPGDATMKDM4E | |
| SCHEMBL21625481 | 0.72 | GAA (0.36) | LNPEPALDH1A1HPGDATMKDM4E | |
| SCHEMBL28797271 | 0.72 | NLRP3 (0.43) | ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL28527506 | 0.71 | GAA (0.33) | ALDH1A1HPGDATMKDM4EGAA | |
| SCHEMBL24975328 | 0.71 | DRD4 (0.37) | RXFP1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL21127855 | 0.71 | DRD4 (0.31) | RXFP1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL21625479 | 0.70 | NLRP3 (0.39) | NPSR1ATMSMN1; SMN2 | |
| SCHEMBL28636651 | 0.70 | TLR9 (0.32) | — | |
| SCHEMBL28641253 | 0.69 | NPSR1 (0.38) | NPSR1ALDH1A1HPGDATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112437683-A | Sulfonylurea compounds useful as inhibitors of interleukin-1 activity | 豪夫迈·罗氏有限公司 | 2021-03-02 | — | — | CN | disclosed |