Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.77 |
| ▸ | THRB | P10828 | 9/20 | 0.77 |
| ▸ | RARB | P10826 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | RARA | P10276 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | MTOR | P42345 | 1/20 | 0.69 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.63 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849969 | 1.00 | THRA (0.77) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL2831001 | 0.93 | THRA (0.69) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL2564366 | 0.92 | RARB (0.67) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL13950912 | 0.92 | RARB (0.67) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL7330661 | 0.89 | THRA (0.69) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL7651082 | 0.88 | THRA (0.69) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL15453509 | 0.88 | THRA (0.69) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL16536411 | 0.88 | THRA (0.69) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL7652503 | 0.88 | THRA (0.69) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL7649277 | 0.88 | THRA (0.69) | THRATHRBRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816520-B2 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-10-19 | — | — | US | disclosed |
| EP-1753747-B1 | 5,6-DIPHENYL-1,2,4-TRIAZINIC DIMERIC DERIVATIVES AND THE USE THEREOF IN THE FORM OF SUN-PROTECTIVE AGENTS | FABRE PIERRE DERMO COSMETIQUE (FR) | 2010-01-13 | — | — | EP | disclosed |
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | TYR, H1-0, TELO2 | THRA 644/4885THRB 995/4885RARB 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.