Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.69 |
| ▸ | THRB | P10828 | 9/20 | 0.69 |
| ▸ | RARB | P10826 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RARA | P10276 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.60 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853869 | 0.89 | THRA (0.77) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL2849969 | 0.89 | THRA (0.77) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL11431401 | 0.88 | CES2 (0.68) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL28433161 | 0.85 | CES2 (0.68) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL2831001 | 0.83 | THRA (0.69) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL10883866 | 0.82 | THRA (0.75) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL11435461 | 0.82 | THRA (0.75) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL11427685 | 0.82 | THRA (0.75) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL8903148 | 0.82 | THRA (0.75) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL13267849 | 0.82 | THRA (0.75) | THRATHRBRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-B1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-6265536-B1 | MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6107458-A | FUNGICIDE WHICH IS BETA-1,3-GLYCAN SYNTHASE INHIBITOR; FOR PROPHYLAXIS AND TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS LIKE PNEUMONIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |
| WO-1996011210-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |