Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MLYCD | O95822 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21679321 | 0.84 | EGLN1 (0.61) | EGLN1CTSKGAATDP1MGAM | |
| SCHEMBL7737241 | 0.84 | EGLN1 (0.55) | EGLN1EPHX2GAAMGAMSI | |
| SCHEMBL5205850 | 0.80 | GAA (0.45) | CTSKEPHX2GAAMLYCDMGAM | |
| SCHEMBL13991916 | 0.79 | MLYCD (0.39) | CTSKEPHX2GAAMLYCDTDP1 | |
| SCHEMBL4960461 | 0.79 | MLYCD (0.40) | EPHX2GAAMLYCDTDP1MAPT | |
| SCHEMBL21728958 | 0.79 | TDP1 (0.63) | EGLN1GAATDP1MAPTMEN1 | |
| SCHEMBL10259138 | 0.79 | GAA (0.47) | CTSKGAAMLYCDTDP1MGAM | |
| SCHEMBL12495312 | 0.78 | EGLN1 (0.65) | EGLN1GAATDP1MGAMSI | |
| SCHEMBL19451081 | 0.77 | TET2 (0.47) | EGLN1EPHX2GAAMLYCDTDP1 | |
| Hydrochloric Acid SCHEMBL7451357 | 0.77 | MLYCD (0.41) | CTSKEPHX2GAAMLYCDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074808-B | Therapeutic compounds as orexin-1 receptor inhibitors | 希四克斯探索有限公司 | 2021-03-02 | — | — | CN | disclosed |