Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17161225 | 0.86 | HTR2A (0.44) | HTR2ADPP8DPP9MGLLBMP1 | |
| SCHEMBL15669378 | 0.82 | HTR2A (0.40) | HTR2ABMP1TGM2 | |
| SCHEMBL14957817 | 0.81 | HTR2A (0.39) | HTR2ADPP8DPP9MGLLBMP1 | |
| SCHEMBL31009020 | 0.78 | HTR2A (0.49) | HTR2ADPP8DPP9MGLLHTT | |
| SCHEMBL15631789 | 0.78 | HTR2A (0.49) | HTR2ADPP8DPP9MGLLHTT | |
| SCHEMBL28531327 | 0.77 | REN (0.32) | — | |
| SCHEMBL15669247 | 0.77 | HTR2A (0.35) | HTR2ADPP8DPP9BMP1TGM2 | |
| SCHEMBL16949548 | 0.76 | HTR2A (0.52) | HTR2ADPP8DPP9MGLLHTT | |
| SCHEMBL15676508 | 0.76 | FAP (0.36) | HTR2ADPP8DPP9BMP1HTT | |
| SCHEMBL18949805 | 0.74 | HTR2A (0.52) | HTR2ADPP8DPP9MGLLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795203-B | Stability modulating linkers for antibody drug conjugates | 辉瑞公司 | 2021-01-26 | — | — | CN | disclosed |