Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29822513 | 0.83 | FFAR4 (0.32) | HTTKMT2A | |
| SCHEMBL28525953 | 0.83 | FFAR4 (0.32) | HTTKMT2A | |
| Hydrochloric Acid SCHEMBL28542838 | 0.77 | MAPT (0.47) | MAPTGAATDP1PKMSMN1; SMN2 | |
| SCHEMBL19436434 | 0.76 | MAPT (0.49) | MAPTGAATDP1PKMSMN1; SMN2 | |
| SCHEMBL19436435 | 0.76 | MAPT (0.49) | MAPTGAATDP1PKMSMN1; SMN2 | |
| SCHEMBL28510943 | 0.76 | MAPT (0.46) | MAPTGAATDP1PKMSMN1; SMN2 | |
| SCHEMBL29200491 | 0.75 | LMNA (0.47) | MAPTGAAKDM4ETDP1PKM | |
| SCHEMBL5517552 | 0.75 | LMNA (0.42) | MAPTGAAKDM4ELMNAPOLB | |
| SCHEMBL2695937 | 0.75 | LMNA (0.42) | MAPTGAAKDM4ELMNAPOLB | |
| SCHEMBL19437401 | 0.75 | MAPT (0.51) | MAPTGAATDP1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492212-B2 | Substituted pyrazolecarboxamides as sting activators | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-12-09 | — | — | US | disclosed |
| CN-114981273-B | Heterocyclic amide compound, pharmaceutically acceptable salt thereof, preparation method and application thereof | 中国科学院上海药物研究所 | 2024-03-01 | — | — | CN | disclosed |
| CN-114981273-A | Heterocyclic amide compound, pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国科学院上海药物研究所 | 2022-08-30 | — | — | CN | disclosed |
| EP-4032890-A1 | HETEROCYCLIC AMIDE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2022-07-27 | — | — | EP | disclosed |
| CN-112521394-A | Heterocyclic amide compound, pharmaceutically acceptable salt thereof, preparation method and application thereof | 中国药科大学 | 2021-03-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12492212-B2 | Substituted pyrazolecarboxamides as sting activators | STING1, CGAS, TBK1 | MAPT 4716/4885GAA 1114/4885KDM4E 3154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.