Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971626 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BGAAKMT2AMAPT | |
| SCHEMBL22835340 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BGAAKMT2AMAPT | |
| SCHEMBL8912151 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2BGAAKMT2AMAPT | |
| SCHEMBL20120713 | 0.83 | KMT2A (0.40) | ITGB3ITGA2BGAAKMT2AL3MBTL1 | |
| SCHEMBL2013070 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BGAAKMT2AL3MBTL1 | |
| SCHEMBL17672505 | 0.83 | GAA (0.41) | GAAKMT2AMAPTTHRBATM | |
| SCHEMBL4115177 | 0.82 | ALDH1A1 (0.43) | ITGB3ITGA2BKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7017334 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2008270 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BGAAL3MBTL1ALDH1A1 | |
| SCHEMBL6319049 | 0.81 | HPGD (0.46) | ITGB3ITGA2BGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025159-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |