Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.53 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.40 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28539694 | 1.00 | BACE1 (0.53) | BACE1BACE2LTA4HRENFOLH1 | |
| SCHEMBL21261602 | 0.83 | LTA4H (0.43) | BACE1LTA4HFOLH1FNTAFNTB | |
| SCHEMBL21261601 | 0.83 | LTA4H (0.43) | BACE1LTA4HFOLH1FNTAFNTB | |
| SCHEMBL21246660 | 0.82 | LMNA (0.49) | LTA4HFOLH1FNTAFNTBPGGT1B | |
| SCHEMBL21246659 | 0.82 | LMNA (0.49) | LTA4HFOLH1FNTAFNTBPGGT1B | |
| SCHEMBL28531585 | 0.81 | BACE1 (0.47) | BACE1FOLH1NAALAD2RIMKLACTSD | |
| SCHEMBL21261658 | 0.81 | BACE1 (0.47) | BACE1FOLH1NAALAD2RIMKLACTSD | |
| SCHEMBL28552630 | 0.81 | BACE1 (0.41) | BACE1LTA4HFNTAFNTBPGGT1B | |
| SCHEMBL28552633 | 0.81 | BACE1 (0.41) | BACE1LTA4HFNTAFNTBPGGT1B | |
| SCHEMBL11127815 | 0.81 | FOLH1 (0.50) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017555-B | Beta-hydroxybutyryl-amino acid compound and preparation method and application thereof | 郑州海斯威生物技术有限公司 | 2021-03-26 | — | — | CN | disclosed |