Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16290043 | 0.98 | TGFBR1 (0.47) | TGFBR1RXFP1TDP1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL28998896 | 0.96 | TGFBR1 (0.46) | TGFBR1RXFP1TDP1TSHRALDH1A1 | |
| Trimethylammonium SCHEMBL28073605 | 0.90 | TGFBR1 (0.42) | TGFBR1RXFP1TDP1 | |
| SCHEMBL11009489 | 0.82 | TGFBR1 (0.44) | TGFBR1RXFP1TDP1TSHRALDH1A1 | |
| SCHEMBL554944 | 0.78 | TGFBR1 (0.48) | TGFBR1RXFP1TSHRALDH1A1 | |
| SCHEMBL9193899 | 0.78 | TGFBR1 (0.59) | TGFBR1RXFP1TDP1TSHRALDH1A1 | |
| SCHEMBL18641077 | 0.78 | TGFBR1 (0.48) | TGFBR1RXFP1TDP1TSHRALDH1A1 | |
| SCHEMBL717760 | 0.78 | — | — | |
| SCHEMBL22768287 | 0.77 | TGFBR1 (0.47) | TGFBR1RXFP1TDP1TSHRALDH1A1 | |
| SCHEMBL9500975 | 0.77 | TGFBR1 (0.47) | TGFBR1RXFP1TDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112794518-B | Pretreatment system and treatment method for chemical synthesis pharmaceutical high-concentration wastewater | 华夏碧水环保科技有限公司北京分公司 | 2021-09-28 | — | — | CN | claimed |
| CN-112794518-A | Pretreatment system and treatment method for chemical synthesis pharmaceutical high-concentration wastewater | 华夏碧水环保科技有限公司北京分公司 | 2021-05-14 | — | — | CN | claimed |
| CN-112499842-B | Pretreatment system and pretreatment method for chemical synthesis pharmaceutical high-salt high-concentration wastewater | 华夏碧水环保科技有限公司北京分公司 | 2021-05-07 | — | — | CN | claimed |
| CN-112390479-B | Chemical synthesis pharmaceutical wastewater treatment system and treatment method | 华夏碧水环保科技有限公司北京分公司 | 2021-05-07 | — | — | CN | claimed |
| CN-112499842-A | Pretreatment system and pretreatment method for chemical synthesis pharmaceutical high-salt high-concentration wastewater | 华夏碧水环保科技有限公司北京分公司 | 2021-03-16 | — | — | CN | claimed |
| CN-112390479-A | Chemical synthesis pharmaceutical wastewater treatment system and treatment method | 华夏碧水环保科技有限公司北京分公司 | 2021-02-23 | — | — | CN | claimed |
| CN-112794518-B | Pretreatment system and treatment method for chemical synthesis pharmaceutical high-concentration wastewater | 华夏碧水环保科技有限公司北京分公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-112794518-A | Pretreatment system and treatment method for chemical synthesis pharmaceutical high-concentration wastewater | 华夏碧水环保科技有限公司北京分公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-112499842-B | Pretreatment system and pretreatment method for chemical synthesis pharmaceutical high-salt high-concentration wastewater | 华夏碧水环保科技有限公司北京分公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112390479-B | Chemical synthesis pharmaceutical wastewater treatment system and treatment method | 华夏碧水环保科技有限公司北京分公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112499842-A | Pretreatment system and pretreatment method for chemical synthesis pharmaceutical high-salt high-concentration wastewater | 华夏碧水环保科技有限公司北京分公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-112390479-A | Chemical synthesis pharmaceutical wastewater treatment system and treatment method | 华夏碧水环保科技有限公司北京分公司 | 2021-02-23 | — | — | CN | disclosed |