SCHEMBL9500975

SCHEMBL9500975

C=C(C)C(=O)NC(C)CC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.47
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
RXFP1 Q9HBX9 1/20 0.35
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9193899 0.80 TGFBR1 (0.59) TGFBR1ALDH1A1TDP1RXFP1TSHR
SCHEMBL18641077 0.80 TGFBR1 (0.48) TGFBR1ALDH1A1TDP1RXFP1TSHR
SCHEMBL554944 0.80 TGFBR1 (0.48) TGFBR1ALDH1A1RXFP1TSHR
SCHEMBL22768287 0.78 TGFBR1 (0.47) TGFBR1ALDH1A1TDP1RXFP1TSHR
SCHEMBL16290043 0.78 TGFBR1 (0.47) TGFBR1ALDH1A1TDP1RXFP1TSHR
SCHEMBL24495943 0.77 TGFBR1 (0.46) TGFBR1ALDH1A1RXFP1TSHR
SCHEMBL472264 0.77 TGFBR1 (0.46) TGFBR1ALDH1A1TDP1RXFP1
SCHEMBL4037645 0.77 TGFBR1 (0.46) TGFBR1ALDH1A1RXFP1TSHR
SCHEMBL1629827 0.77 TGFBR1 (0.46) TGFBR1ALDH1A1RXFP1TSHR
Bicarbonate SCHEMBL9862026 0.77 TGFBR1 (0.50) TGFBR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271797-B1 SILVER HALIDE COLOR LIGHT SENSITIVE ELEMENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-26 EP disclosed
US-4990435-A Stable polymeric coating MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-05 US disclosed
EP-0226129-B1 SILVER HALIDE PHOTOGRAPHIC ELEMENT, PHOTOGRAPHIC COATING COMPOSITION AND PROCESS TO PREPARE AN AQUEOUS DISPERSION OF A HYDROPHOBIC COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-23 EP disclosed
US-4822728-A CONTROLLED SMEARING OF IMAGE-FORMING DYE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-04-18 US disclosed
EP-0271797-A2 Silver halide color light sensitive elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-22 EP disclosed
EP-0226129-A2 Silver halide photographic element, photographic coating composition and process to prepare an aqueous dispersion of a hydrophobic compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-06-24 EP disclosed
US-4637467-A INJECTION OF N-3-OXOHYDROCARBON-SUBSTITUTED ACRYLAMIDES PHILLIPS PETROLEUM COMPANY (US) 1987-01-20 US disclosed
US-3941836-A SOLUBILIZERS, PLASTICIZER, UV ABSORBER THE LUBRIZOL CORPORATION (US) 1976-03-02 US disclosed