Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28912557 | 0.81 | MEN1 (1.00) | MAPTMEN1KMT2AMAOBHPGD | |
| SCHEMBL13779437 | 0.81 | ALOX12 (0.54) | MAPTMEN1KMT2AALOX12HPGD | |
| SCHEMBL13779436 | 0.81 | MTNR1A (0.51) | MAPTMEN1KMT2A | |
| SCHEMBL5452784 | 0.79 | KMT2A (0.63) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL1520659 | 0.78 | MAOB (1.00) | MAPTMEN1KMT2AMAOBMAOA | |
| SCHEMBL31674408 | 0.78 | MAOB (0.62) | MAPTMEN1KMT2AMAOBMAOA | |
| SCHEMBL5524250 | 0.77 | MTNR1A (0.57) | MAPTMEN1KMT2AHPGD | |
| SCHEMBL30388749 | 0.77 | MAOB (0.83) | MAPTMEN1KMT2AMAOBMAOA | |
| SCHEMBL30849357 | 0.76 | MAPT (0.49) | MAPTMEN1KMT2AMAOBMAOA | |
| SCHEMBL29207165 | 0.76 | MAPT (0.49) | MAPTMEN1KMT2AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574082-B | Preparation method of thiourea alkylated derivative | 西华大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-112574082-A | Preparation method of thiourea alkylated derivative | 西华大学 | 2021-03-30 | — | — | CN | disclosed |