Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 5/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 9/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19513999 | 1.00 | KDM5A (0.42) | KDM5AL3MBTL3L3MBTL1MBTD1POLB | |
| SCHEMBL17672423 | 0.83 | KDM5A (0.57) | KDM5AL3MBTL3L3MBTL1KDM4EKMT2A | |
| SCHEMBL26114140 | 0.79 | L3MBTL3 (0.38) | KDM5AL3MBTL3L3MBTL1MBTD1POLB | |
| SCHEMBL26114145 | 0.79 | L3MBTL3 (0.38) | KDM5AL3MBTL3L3MBTL1MBTD1POLB | |
| SCHEMBL26118190 | 0.79 | L3MBTL3 (0.38) | KDM5AL3MBTL3L3MBTL1MBTD1POLB | |
| SCHEMBL30912557 | 0.78 | DHODH (0.40) | L3MBTL3L3MBTL1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL28541089 | 0.78 | KDM5A (0.54) | KDM5AL3MBTL3L3MBTL1MBTD1KDM4E | |
| SCHEMBL19531954 | 0.75 | IL4I1 (0.39) | L3MBTL3L3MBTL1POLBKDM4EALDH1A1 | |
| SCHEMBL17682584 | 0.73 | KDM5A (0.55) | KDM5A | |
| SCHEMBL19513964 | 0.73 | KDM5A (0.55) | KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107912040-B | Pyrrolidine amide compounds as histone demethylase inhibitors | 基因泰克公司 | 2021-04-06 | — | — | CN | disclosed |