Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 17/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540314 | 1.00 | MC2R (0.55) | MC2RPDE10AMAPTDHODH | |
| SCHEMBL28909259 | 0.93 | MC2R (0.54) | MC2R | |
| SCHEMBL28909261 | 0.93 | MC2R (0.54) | MC2R | |
| SCHEMBL28528906 | 0.92 | MC2R (0.55) | MC2R | |
| SCHEMBL28528913 | 0.89 | MC2R (0.49) | MC2RPDE10A | |
| SCHEMBL31188835 | 0.86 | MC2R (0.73) | MC2RPDE10AMAPT | |
| SCHEMBL21700880 | 0.86 | MC2R (0.73) | MC2RPDE10AMAPT | |
| SCHEMBL21700923 | 0.86 | MC2R (0.73) | MC2RPDE10AMAPT | |
| SCHEMBL28543256 | 0.84 | MC2R (0.72) | MC2R | |
| SCHEMBL28543255 | 0.84 | MC2R (0.72) | MC2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533904-A | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-112533904-A | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2021-03-19 | — | — | CN | disclosed |