Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 15/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909259 | 1.00 | MC2R (0.54) | MC2RTP53LMNACYP46A1 | |
| SCHEMBL28540313 | 0.93 | MC2R (0.55) | MC2R | |
| SCHEMBL28540314 | 0.93 | MC2R (0.55) | MC2R | |
| SCHEMBL28528906 | 0.92 | MC2R (0.55) | MC2RLMNA | |
| SCHEMBL28528913 | 0.91 | MC2R (0.49) | MC2R | |
| SCHEMBL31188837 | 0.86 | MC2R (0.73) | MC2R | |
| SCHEMBL21700901 | 0.86 | MC2R (0.73) | MC2R | |
| SCHEMBL21700903 | 0.86 | MC2R (0.73) | MC2R | |
| SCHEMBL28543255 | 0.85 | MC2R (0.72) | MC2R | |
| SCHEMBL28543256 | 0.85 | MC2R (0.72) | MC2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533904-A | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-112533904-A | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2021-03-19 | — | — | CN | disclosed |