SCHEMBL2854053

SCHEMBL2854053

C=CC(=O)OCC(COC(=O)C=C)(COC(=O)C=C)COP(=O)(O)OCC(COC(=O)C=C)(COC(=O)C=C)COC(=O)C=C

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
TP53 P04637 3/20 0.58
HIF1A Q16665 3/20 0.58
CYP3A4 P08684 2/20 0.58
MAPK1 P28482 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
THRB P10828 2/20 0.41
TSHR P16473 7/20 0.39
HSD17B10 Q99714 1/20 0.39
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2863125 0.90 THRB (0.55) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL1054268 0.89 ALDH1A1 (0.58) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL890489 0.84 ALDH1A1 (0.53) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL101492 0.84 ALDH1A1 (0.78) ALDH1A1TP53HIF1ACYP3A4MAPK1
Butadiene SCHEMBL10409182 0.80 ALDH1A1 (0.72) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL15032909 0.79 ALDH1A1 (0.60) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL268293 0.78 ALDH1A1 (0.69) ALDH1A1TP53HIF1ACYP3A4MAPK1
Acrylic Acid SCHEMBL9170386 0.78 ALDH1A1 (0.69) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL20690222 0.78 ALDH1A1 (0.69) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL19652444 0.78 ALDH1A1 (0.69) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1381861-B1 PROCESSES FOR PRODUCING COATED MAGNETIC MICROPARTICLES AND USES THEREOF CAPITALBIO CORP (CN) 2010-01-20 EP claimed
EP-1381861-A4 PROCESSES FOR PRODUCING COATED MAGNETIC MICROPARTICLES AND USES THEREOF CAPITAL BIOCHIP CO LTD (CN) 2005-10-19 EP claimed
US-20050009002-A1 Processes for producing coated magnetic microparticles and uses thereof AVIVA BIOSCIENCES CORPORATION 2005-01-13 US claimed
EP-1381861-A1 PROCESSES FOR PRODUCING COATED MAGNETIC MICROPARTICLES AND USES THEREOF Aviva Biosciences Corporation (US) 2004-01-21 EP claimed
WO-2002075309-A1 PROCESSES FOR PRODUCING COATED MAGNETIC MICROPARTICLES AND USES THEREOF AVIVA BIOSCIENCES CORPORATION (US) 2002-09-26 WO claimed
EP-1381861-B1 PROCESSES FOR PRODUCING COATED MAGNETIC MICROPARTICLES AND USES THEREOF CAPITALBIO CORP (CN) 2010-01-20 EP disclosed
EP-1381861-A4 PROCESSES FOR PRODUCING COATED MAGNETIC MICROPARTICLES AND USES THEREOF CAPITAL BIOCHIP CO LTD (CN) 2005-10-19 EP disclosed
US-20050009002-A1 Processes for producing coated magnetic microparticles and uses thereof AVIVA BIOSCIENCES CORPORATION 2005-01-13 US disclosed
EP-1381861-A1 PROCESSES FOR PRODUCING COATED MAGNETIC MICROPARTICLES AND USES THEREOF Aviva Biosciences Corporation (US) 2004-01-21 EP disclosed
WO-2002075309-A1 PROCESSES FOR PRODUCING COATED MAGNETIC MICROPARTICLES AND USES THEREOF AVIVA BIOSCIENCES CORPORATION (US) 2002-09-26 WO disclosed