Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18131594 | 0.90 | NPC1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL30275281 | 0.86 | SMN1; SMN2 (0.53) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL29498959 | 0.85 | NPC1 (0.51) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| Guanabenz SCHEMBL31129061 | 0.81 | POLB (0.53) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| Acetic Acid SCHEMBL21519491 | 0.79 | SMN1; SMN2 (0.56) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL30275294 | 0.78 | MAPT (0.49) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL21519625 | 0.76 | POLB (0.44) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| Guanabenz SCHEMBL21519448 | 0.76 | CYP1A2 (0.49) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL21519513 | 0.75 | GAA (0.44) | MAPTSMN1; SMN2HPGDHTTMAOB | |
| SCHEMBL30275295 | 0.75 | HTT (0.39) | MAPTSMN1; SMN2HPGDHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709291-B | Inhibitors and uses thereof | 医疗研究局 | 2021-03-12 | — | — | CN | disclosed |