Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.51 |
| ▸ | MELK | Q14680 | 1/20 | 0.51 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | YWHAZ | P63104 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL21519491 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAKMT2AALDH1A1NPSR1 | |
| SCHEMBL16993764 | 0.89 | LMNA (0.58) | SMN1; SMN2LMNAKMT2AALDH1A1NPSR1 | |
| SCHEMBL31105625 | 0.89 | LMNA (0.58) | SMN1; SMN2LMNAKMT2AALDH1A1NPSR1 | |
| SCHEMBL16993763 | 0.89 | LMNA (0.58) | SMN1; SMN2LMNAKMT2AALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL5703099 | 0.88 | LMNA (0.57) | SMN1; SMN2LMNAKMT2AALDH1A1NPSR1 | |
| SCHEMBL29498959 | 0.88 | NPC1 (0.51) | SMN1; SMN2LMNAKMT2AALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL5703097 | 0.88 | LMNA (0.57) | SMN1; SMN2LMNAKMT2AALDH1A1NPSR1 | |
| SCHEMBL28540804 | 0.86 | NPC1 (0.43) | SMN1; SMN2LMNAKMT2AALDH1A1NPSR1 | |
| Guanabenz SCHEMBL31129061 | 0.83 | POLB (0.53) | SMN1; SMN2KMT2AALDH1A1NPSR1NPC1 | |
| Acetic Acid SCHEMBL21519488 | 0.82 | LMNA (0.61) | SMN1; SMN2LMNAKMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107820518-B | Methods for selecting phosphatase selective inhibitors and non-selective phosphatase inhibitors | 英国研究与创新署 | 2023-04-21 | — | — | CN | claimed |
| CN-107820518-B | Methods for selecting phosphatase selective inhibitors and non-selective phosphatase inhibitors | 英国研究与创新署 | 2023-04-21 | — | — | CN | disclosed |