Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620015 | 0.82 | FABP7 (0.45) | FABP7FABP3FABP5SMN1; SMN2KDM4E | |
| SCHEMBL27996039 | 0.81 | ELANE (0.46) | FABP7FABP3FABP5SMN1; SMN2HTT | |
| SCHEMBL23867037 | 0.79 | FABP7 (0.43) | FABP7FABP3FABP5SMN1; SMN2KDM4E | |
| SCHEMBL10180088 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2KDM4EHPGDPPARGPPARA | |
| SCHEMBL7326080 | 0.78 | FABP7 (0.42) | FABP7FABP3FABP5HTTKDM4E | |
| SCHEMBL7866345 | 0.77 | FABP7 (0.50) | FABP7FABP3FABP5SMN1; SMN2KDM4E | |
| SCHEMBL10601943 | 0.77 | FABP7 (0.44) | FABP7FABP3FABP5SMN1; SMN2KDM4E | |
| SCHEMBL12256164 | 0.76 | KDM4E (0.61) | SMN1; SMN2HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL7866349 | 0.75 | FABP7 (0.53) | FABP7FABP3FABP5SMN1; SMN2KDM4E | |
| SCHEMBL25519396 | 0.75 | KMT2A (0.43) | FABP7FABP3FABP5HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023331-A | Synthesis method of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic acid | 馨仝(上海)生物科技有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-116023331-A | Synthesis method of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic acid | 馨仝(上海)生物科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-112321553-B | Method for synthesizing 3-position difluoromethyl substituted coumarin derivative from aryl alkyne acid ester | 天津科技大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-112321553-A | Method for synthesizing 3-position difluoromethyl substituted coumarin derivative from aryl alkyne acid ester | 天津科技大学 | 2021-02-05 | — | — | CN | disclosed |