Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28551339 | 0.81 | KMT2A (0.40) | TSHRIDO1KCNH2ALDH1A1MAPT | |
| SCHEMBL5278772 | 0.80 | HPGD (0.40) | MEN1KMT2AMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL1849006 | 0.79 | HPGD (0.42) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL6929124 | 0.78 | KDM4E (0.44) | KDM4ETSHRALDH1A1CREBBPMAPT | |
| SCHEMBL4939722 | 0.78 | LMNA (0.47) | KDM4EALDH1A1MAPTHSD17B10STAT6 | |
| Hydrochloric Acid SCHEMBL8686203 | 0.77 | KDM4E (0.43) | KDM4ETSHRIDO1KCNH2ALDH1A1 | |
| SCHEMBL20144010 | 0.76 | NOTUM (0.41) | KDM4EALDH1A1TP53MAPK1RECQL | |
| SCHEMBL16837367 | 0.76 | NOTUM (0.41) | KDM4EALDH1A1TP53MAPK1RECQL | |
| SCHEMBL22563238 | 0.76 | KMT2A (0.33) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 | |
| SCHEMBL20242724 | 0.75 | LMNA (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017573-B | Process for preparing 4-methylenepiperidine or acid addition salt thereof | 山东特珐曼药业有限公司 | 2021-03-26 | — | — | CN | disclosed |