Butane

Butane

SCHEMBL2854155

CCCC.O=C(O)CCC(=O)OCC1CCCCC1

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.87
ALDH1A1 P00352 2/20 0.50
THRA P10827 2/20 0.40
THRB P10828 2/20 0.40
NAAA Q02083 2/20 0.38
SLC1A3 P43003 2/20 0.37
SLC1A2 P43004 2/20 0.37
SLC1A1 P43005 2/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37
FFAR1 O14842 1/20 0.36
MMP3 P08254 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715628 0.93 LMNA (1.00) LMNAALDH1A1THRATHRBSLC1A3
SCHEMBL27471006 0.91 LMNA (0.96) LMNAALDH1A1THRATHRBSLC1A3
SCHEMBL27469994 0.88 LMNA (0.89) LMNAALDH1A1THRATHRBSLC1A3
SCHEMBL1058293 0.86 LMNA (0.68) LMNAALDH1A1NAAASLC1A3SLC1A2
SCHEMBL9208258 0.86 LMNA (0.85) LMNAALDH1A1THRATHRBSLC1A3
SCHEMBL12133169 0.84 LMNA (0.71) LMNAALDH1A1THRBMEN1MAPT
SCHEMBL27471005 0.84 LMNA (0.81) LMNAALDH1A1SLC1A3SLC1A2SLC1A1
SCHEMBL10747177 0.83 LMNA (0.80) LMNAALDH1A1THRATHRBNAAA
SCHEMBL13369423 0.83 LMNA (0.64) LMNANAAA
SCHEMBL28258512 0.81 LMNA (0.77) LMNAALDH1A1THRATHRBNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed
US-8822366-B2 Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin MITSUI CHEMICALS, INC. (JP) 2014-09-02 US disclosed
EP-2206731-B1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2013-08-28 EP disclosed
US-20100227991-A1 SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN MITSUI CHEMICALS, INC. (JP) 2010-09-09 US disclosed
EP-2206731-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-07-14 EP disclosed