Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543772 | 1.00 | GLA (0.39) | GLAPDK1KDM4EALDH1A1LMNA | |
| SCHEMBL321971 | 0.81 | — | — | |
| SCHEMBL23581707 | 0.78 | PDK1 (0.46) | PDK1KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL20565204 | 0.78 | PDK1 (0.46) | PDK1KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL2210266 | 0.78 | BRD4 (0.44) | ALDH1A1POLB | |
| SCHEMBL28542205 | 0.77 | HTT (0.61) | — | |
| SCHEMBL26077287 | 0.77 | HTT (0.61) | — | |
| SCHEMBL23581717 | 0.77 | PDK1 (0.40) | PDK1ALDH1A1 | |
| SCHEMBL23581716 | 0.77 | PDK1 (0.40) | PDK1ALDH1A1 | |
| SCHEMBL2125917 | 0.76 | LMNA (0.50) | KDM4EALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |