Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541917 | 0.91 | TDP1 (0.53) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL28554560 | 0.90 | TDP1 (0.58) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL28551024 | 0.87 | LMNA (0.50) | TDP1LMNAKMT2AALDH1A1POLB | |
| SCHEMBL9801767 | 0.87 | HDAC3 (0.51) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL28546668 | 0.86 | LMNA (0.49) | TDP1LMNAKMT2AALDH1A1POLB | |
| SCHEMBL27544808 | 0.84 | TDP1 (0.68) | TDP1LMNAALDH1A1POLBHPGD | |
| SCHEMBL5579337 | 0.83 | BCHE (0.45) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL11280450 | 0.83 | BCHE (0.57) | LMNASMN1; SMN2HTT | |
| SCHEMBL28537066 | 0.81 | MAPT (0.53) | TDP1LMNAKMT2AALDH1A1POLB | |
| SCHEMBL7896669 | 0.81 | POLB (0.51) | TDP1POLBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553703-B | Catalyst component for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-109553706-B | Catalyst component for olefin polymerization, catalyst and application | 中国石油化工股份有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-109553711-B | Catalyst component for olefin polymerization and catalyst thereof | 中国石油化工股份有限公司 | 2021-04-13 | — | — | CN | disclosed |