SCHEMBL28544168

SCHEMBL28544168

NC(=O)C1C=CC=CN1I

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10905580 0.66 LMNA (0.35)
SCHEMBL28070198 0.62
SCHEMBL6278266 0.59
SCHEMBL18459775 0.59
SCHEMBL28824489 0.59
SCHEMBL23659091 0.59
SCHEMBL10368402 0.59
SCHEMBL1845752 0.58
SCHEMBL28180466 0.57
SCHEMBL10068259 0.53 TSHR (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112601740-A Radioactive compounds for the treatment of melanoma and uses thereof 全南大学校产学协力团 2021-04-02 CN claimed
US-11504439-B2 Radioactive compound for diagnosis of malignant melanoma and use thereof INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) 2022-11-22 US disclosed
CN-112601740-A Radioactive compounds for the treatment of melanoma and uses thereof 全南大学校产学协力团 2021-04-02 CN disclosed