Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934481 | 0.89 | POLB (0.45) | POLBALDH1A1TSHRLMNAGPR119 | |
| SCHEMBL2595703 | 0.82 | POLB (0.54) | POLBGPR119KDM4EMAPTTHRB | |
| SCHEMBL1303092 | 0.76 | POLB (0.50) | POLBGPR119KDM4EMEN1KMT2A | |
| SCHEMBL28341942 | 0.74 | HTR2B (0.40) | POLBALDH1A1GPR119KDM4EMAPT | |
| SCHEMBL29008821 | 0.73 | MEN1 (0.42) | ALDH1A1TSHRLMNAGRM5MAPT | |
| SCHEMBL27934478 | 0.73 | SSTR4 (0.37) | POLBGPR119 | |
| SCHEMBL27703983 | 0.70 | TSHR (0.40) | POLBALDH1A1TSHRLMNAGRM5 | |
| SCHEMBL28547371 | 0.70 | GPR119 (0.41) | POLBTSHRLMNAGPR119KDM4E | |
| SCHEMBL31556666 | 0.68 | POLB (0.41) | POLBALDH1A1TSHRLMNAGPR119 | |
| SCHEMBL30639338 | 0.68 | GPR119 (0.44) | POLBALDH1A1LMNAGPR119GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566637-A | GLP-1 receptor agonists and uses thereof | 辉瑞公司 | 2021-03-26 | — | — | CN | disclosed |