Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30916940 | 0.74 | PKM (0.51) | POLBPKMNPC1RAB9AMAPT | |
| SCHEMBL15577575 | 0.73 | SMN1; SMN2 (0.57) | POLBPKMNPC1RAB9AMAPT | |
| SCHEMBL30748254 | 0.72 | SMN1; SMN2 (0.55) | POLBPKMMAPTSMN1; SMN2HTT | |
| SCHEMBL20560374 | 0.72 | SMN1; SMN2 (0.51) | POLBPKMMAPTSMN1; SMN2HTT | |
| SCHEMBL8955980 | 0.72 | SMN1; SMN2 (0.55) | POLBPKMMAPTSMN1; SMN2HTT | |
| SCHEMBL5154487 | 0.72 | SMN1; SMN2 (0.55) | POLBPKMNPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL30705784 | 0.70 | SMN1; SMN2 (0.54) | POLBPKMNPC1RAB9AMAPT | |
| SCHEMBL755622 | 0.70 | NPC1 (0.44) | POLBPKMNPC1RAB9AMAPT | |
| SCHEMBL20560322 | 0.68 | ALDH1A1 (0.49) | POLBPKMMAPTSMN1; SMN2HTT | |
| SCHEMBL25474855 | 0.68 | POLB (0.59) | POLBPKMRAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269247-B | Preparation method of buprofezin drug molecule with escherichia coli inhibition effect | 河南科技大学第一附属医院 | 2020-11-24 | — | — | CN | claimed |