SCHEMBL28544453

SCHEMBL28544453

Nc1ccc(OSc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.52
MAPT P10636 6/20 0.44
RAB9A P51151 4/20 0.44
MAOB P27338 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
GAA P10253 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
NPC1 O15118 2/20 0.42
NLRP3 Q96P20 1/20 0.42
CYP3A4 P08684 6/20 0.42
TDP1 Q9NUW8 5/20 0.42
ALDH1A1 P00352 5/20 0.42
TSHR P16473 3/20 0.42
TAAR1 Q96RJ0 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NCOA1 Q15788 1/20 0.40
NCOA3 Q9Y6Q9 1/20 0.40
MAPK1 P28482 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27620437 0.89 SMN1; SMN2 (0.43) MAOAMAPTMAOBSMN1; SMN2ALDH1A1
SCHEMBL5695838 0.84 LTA4H (0.43) MAOAMAPTL3MBTL1SMN1; SMN2TDP1
SCHEMBL11794899 0.82 MEN1 (0.53) MAOAMAPTRAB9AL3MBTL1MEN1
Hydrogen Sulfide SCHEMBL27890271 0.81 LTA4H (0.41) MAOAMAPTL3MBTL1SMN1; SMN2TDP1
SCHEMBL7946309 0.78 MAPT (0.35) MAPTSMN1; SMN2ALDH1A1HSD17B10MAPK1
SCHEMBL28562271 0.78 TSHR (0.42) MAOAMAPTRAB9AMAOBL3MBTL1
SCHEMBL8521078 0.78 NFE2L2 (0.37) MAPTL3MBTL1GAASMN1; SMN2MEN1
SCHEMBL22236903 0.78 CA4 (0.54) MAPTRAB9AL3MBTL1SMN1; SMN2MEN1
Aniline SCHEMBL27459835 0.75 TSHR (0.55) MAOAMAPTRAB9AMAOBL3MBTL1
SCHEMBL3163298 0.74 MAPT (0.35) MAPTSMN1; SMN2ALDH1A1HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113292853-A Resin composition, polyimide resin film, and method for producing same 旭化成株式会社 2021-08-24 CN disclosed
CN-107531996-B Resin composition, polyimide resin film, and method for producing same 旭化成株式会社 2021-03-30 CN disclosed