Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854483 | 0.83 | CHRM2 (0.55) | TAAR1KDM4ESMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL2854409 | 0.83 | CYP1A2 (0.59) | ALDH1A1CYP3A4CYP2D6CYP2C19HTR2A | |
| SCHEMBL17110149 | 0.80 | SCN8A (0.49) | KMT2ACYP3A4CYP2D6CYP2C19ADRB2 | |
| SCHEMBL4037480 | 0.76 | CA1 (0.51) | KDM4EKMT2ACYP2C19ADRB2GAA | |
| SCHEMBL10557535 | 0.76 | CA12 (0.58) | TAAR1ALDH1A1KDM4EGLASMN1; SMN2 | |
| SCHEMBL29444840 | 0.75 | MEN1 (0.56) | TAAR1ALDH1A1KDM4EGLASLC2A4 | |
| SCHEMBL28188921 | 0.75 | GAA (0.74) | ALDH1A1KDM4EGLASMN1; SMN2KMT2A | |
| SCHEMBL2857026 | 0.74 | CHRM2 (0.57) | ALDH1A1KDM4ESMN1; SMN2KMT2ACYP2D6 | |
| SCHEMBL1799518 | 0.74 | CHRM2 (0.45) | TAAR1KDM4ECYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2852240 | 0.73 | MC5R (0.58) | CYP3A4CYP2D6CYP2C19HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |