Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3991512 | 0.80 | GAA (0.63) | CYP1A2CYP2D6CYP2C19CYP3A4GAA | |
| SCHEMBL2852240 | 0.77 | MC5R (0.58) | CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL2854483 | 0.77 | CHRM2 (0.55) | CHRM2CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL5947943 | 0.77 | BCHE (0.55) | CHRM2BCHEKDM4E | |
| SCHEMBL11233431 | 0.75 | MC4R (0.54) | CHRM2CYP1A2CYP2D6CYP2C19FOLH1 | |
| SCHEMBL2037464 | 0.75 | CYP1A2 (0.49) | CHRM2CYP1A2CYP2D6CYP2C19FOLH1 | |
| SCHEMBL2854473 | 0.74 | TAAR1 (0.50) | CYP2D6CYP2C19CYP3A4ADRB2GAA | |
| SCHEMBL2854409 | 0.74 | CYP1A2 (0.59) | CHRM2CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL5947527 | 0.74 | BCHE (0.51) | CHRM2CYP2D6DRD2ADRA1DBCHE | |
| SCHEMBL2483013 | 0.73 | GAA (0.62) | CYP1A2CYP2D6CYP2C19CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951954-B2 | Bezothiazol derivatives as Beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2011-05-31 | — | — | US | disclosed |
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ASTRAZENECA AB (SE) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ADRB2, ADRB1, ADRB3 | CHRM2 90/4885CYP1A2 215/4885CYP2D6 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.