Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.60 |
| ▸ | PPARG | P37231 | 7/20 | 0.60 |
| ▸ | PPARD | Q03181 | 7/20 | 0.60 |
| ▸ | PPARA | Q07869 | 7/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | TLR2 | O60603 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27807130 | 1.00 | AKR1B1 (0.62) | AKR1B1GPR84PPARGPPARDPPARA | |
| Azelaic Acid SCHEMBL29512226 | 0.98 | GPR84 (0.64) | AKR1B1GPR84PPARGPPARDPPARA | |
| Sebacic Acid SCHEMBL28074071 | 0.98 | GPR84 (0.64) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL28335493 | 0.98 | GPR84 (0.64) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL28362550 | 0.98 | GPR84 (0.64) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL30361002 | 0.98 | GPR84 (0.64) | AKR1B1GPR84PPARGPPARDPPARA | |
| Nonanoate SCHEMBL29512132 | 0.96 | GPR84 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL7181665 | 0.94 | AKR1B1 (0.67) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL28861098 | 0.94 | AKR1B1 (0.67) | AKR1B1GPR84PPARGPPARDPPARA | |
| Succinic Acid SCHEMBL29411060 | 0.93 | AKR1B1 (0.52) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574558-A | Anti-floating fiber type glass fiber reinforced bio-based nylon material and preparation method thereof | 海信容声(广东)冰箱有限公司 | 2021-03-30 | — | — | CN | disclosed |