Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662 | 0.88 | — | — | |
| SCHEMBL29446630 | 0.88 | — | — | |
| SCHEMBL28156542 | 0.86 | KDM4E (0.41) | KDM4EMAPTALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL15019884 | 0.86 | KDM4E (0.41) | KDM4EMAPTALDH1A1CHRNB2CHRNA4 | |
| Hydrochlorthiazide SCHEMBL27805829 | 0.73 | KDM4E (0.31) | KDM4EMAPT | |
| SCHEMBL5802653 | 0.72 | CHRNB2 (0.35) | MAPTCHRNB2CHRNA4PDE4ANCOA1 | |
| Benzothiophene SCHEMBL28264756 | 0.69 | ALDH1A1 (0.38) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10921694 | 0.68 | ALDH1A1 (0.38) | KDM4EMAPTALDH1A1DYRK1ANCOA1 | |
| Quinoline SCHEMBL2826037 | 0.67 | ALDH1A1 (0.63) | KDM4EMAPTALDH1A1DYRK1AHTT | |
| Quinoline SCHEMBL28210481 | 0.66 | ALDH1A1 (0.61) | KDM4EMAPTALDH1A1DYRK1AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574223-B | Method for synthesizing 1, 2-dihydrobenzofuran pyridine compound | 中国科学院大连化学物理研究所 | 2021-09-24 | — | — | CN | disclosed |
| CN-112574223-A | Method for synthesizing 1, 2-dihydrobenzofuran pyridine compound | 中国科学院大连化学物理研究所 | 2021-03-30 | — | — | CN | disclosed |