Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16553952 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL789890 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL789912 | 0.90 | ALDH1A1 (0.44) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL15622672 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL22582156 | 0.87 | ALDH1A1 (0.43) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL12274119 | 0.87 | ALDH1A1 (0.43) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL30628342 | 0.87 | ALDH1A1 (0.43) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL790316 | 0.87 | ALDH1A1 (0.41) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL790551 | 0.84 | MEN1 (0.41) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL15765580 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HSD17B10PGRGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108676047-B | HCV polymerase inhibitors | 美迪维尔公司 | 2021-04-02 | — | — | CN | disclosed |