SCHEMBL28544976

SCHEMBL28544976

O=C(O)c1cccc(CSBr)c1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.55
HTT P42858 1/20 0.55
MRGPRX4 Q96LA9 3/20 0.54
AR P10275 1/20 0.54
RAB9A P51151 2/20 0.52
RXFP1 Q9HBX9 1/20 0.49
EPHX1 P07099 1/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2D6 P10635 1/20 0.49
HIF1A Q16665 1/20 0.49
ANPEP P15144 1/20 0.49
ENPEP Q07075 1/20 0.49
CYP1A2 P05177 1/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MEP1B Q16820 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39630 0.85 FOLH1 (0.63) FOLH1SMN1; SMN2HTTMRGPRX4AR
SCHEMBL9976790 0.81 FOLH1 (0.59) FOLH1SMN1; SMN2HTTMRGPRX4AR
SCHEMBL27326766 0.81 FOLH1 (0.59) FOLH1SMN1; SMN2HTTMRGPRX4AR
SCHEMBL46936 0.81 FOLH1 (0.59) FOLH1SMN1; SMN2HTTMRGPRX4AR
SCHEMBL39841 0.79 SMN1; SMN2 (0.56) FOLH1SMN1; SMN2HTTMRGPRX4AR
SCHEMBL6347118 0.79 SMN1; SMN2 (0.60) FOLH1SMN1; SMN2HTTMRGPRX4AR
SCHEMBL12581571 0.79 APEX1 (0.65) FOLH1SMN1; SMN2HTTMRGPRX4AR
SCHEMBL29964040 0.79 FOLH1 (0.66) FOLH1MRGPRX4CYP2C9CYP2D6HIF1A
SCHEMBL40393 0.79 FOLH1 (0.66) FOLH1MRGPRX4CYP2C9CYP2D6HIF1A
SCHEMBL371526 0.78 FOLH1 (0.70) FOLH1MRGPRX4CYP2C9CYP2D6HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108822173-B Fluorescence-labeled cleavable nucleotide, synthesis method and application thereof in DNA sequencing 合肥华纳生物医药科技有限公司 2021-04-02 CN disclosed