SCHEMBL40393

SCHEMBL40393

O=C(O)c1cccc(CBr)c1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.66
MEP1B Q16820 3/20 0.58
MEP1A Q16819 1/20 0.58
MRGPRX4 Q96LA9 2/20 0.54
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
HIF1A Q16665 1/20 0.53
ANPEP P15144 1/20 0.53
ENPEP Q07075 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA6 P23280 1/20 0.52
CA9 Q16790 1/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29964040 1.00 FOLH1 (0.66) FOLH1MEP1BMEP1AMRGPRX4CYP2D6
SCHEMBL6895867 0.85 GSK3B (0.60) FOLH1MEP1BMEP1AMRGPRX4
SCHEMBL29572523 0.85 ATM (0.52) FOLH1MEP1BMEP1ACES2CES1
SCHEMBL2062793 0.85 CES2 (0.48) FOLH1MEP1BMEP1AMRGPRX4CES2
SCHEMBL185962 0.85 ATM (0.52) FOLH1MEP1BMEP1ACES2CES1
SCHEMBL29728644 0.84 L3MBTL1 (0.63) FOLH1CES2CES1
SCHEMBL1815690 0.84 FOLH1 (0.61) FOLH1MEP1BMEP1AMRGPRX4CYP2D6
SCHEMBL435297 0.84 L3MBTL1 (0.63) FOLH1CES2CES1
SCHEMBL70351 0.83 FOLH1 (0.70) FOLH1MEP1BCYP2D6CYP2C9HIF1A
SCHEMBL371526 0.83 FOLH1 (0.70) FOLH1MEP1BMEP1AMRGPRX4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 647 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119955130-A Wear-resistant butyronitrile glove and preparation method thereof 安徽和佳医疗用品科技有限公司 2025-05-09 CN claimed
CN-119529680-A Heat-conducting adhesive for high-heat-conducting double-sided tape and preparation method thereof 浙江凡特科新材料有限公司 2025-02-28 CN claimed
CN-118221674-B Pyrrolo [3,2-b ] pyridine Top/HDAC double-target inhibitor, preparation method, pharmaceutical composition and application thereof 南京市鸿舜医药科技有限公司 2025-01-28 CN claimed
CN-118344284-A Compound with benzamide structure and preparation method and application thereof 杭州医学院 2024-07-16 CN claimed
CN-118221674-A Pyrrolo [3,2-b ] pyridine Top/HDAC double-target inhibitor, preparation method, pharmaceutical composition and application thereof 南京市鸿舜医药科技有限公司 2024-06-21 CN claimed
CN-116716029-B Long-acting antibacterial and antiviral polyester finishing paint and preparation method thereof 中海油常州涂料化工研究院有限公司 2024-04-30 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-116716029-A Long-acting antibacterial and antiviral polyester finishing paint and preparation method thereof 中海油常州涂料化工研究院有限公司 2023-09-08 CN claimed
CN-116462859-A Preparation and application of polyphosphazene hydrogel with inherent antibacterial property 浙江大学 2023-07-21 CN claimed
CN-115466555-B Preparation method of antibacterial surface functional film layer of neodymium-iron-boron magnet 浙江中杭新材料科技有限公司 2023-06-30 CN claimed
CN-112646159-B Preparation method of quaternary ammonium salt modified polyester resin for antibacterial powder coating 浙江光华科技股份有限公司 2022-09-27 CN claimed
CN-112646159-A Preparation method of quaternary ammonium salt modified polyester resin for antibacterial powder coating 浙江光华科技股份有限公司 2021-04-13 CN claimed
US-20040236146-A1 Method for producing 3-bromomethylbenzoic acids BAYER CROPSCIENCE GMBH (DE) 2004-11-25 US claimed
EP-0360246-B1 3-Oxiranyl benzoic acids and derivatives thereof SEARLE & CO (US) 1994-03-30 EP claimed
WO-2025260150-A1 NOVEL N-BENZYL PHTHALIMIDES FOR THE TREATMENT OF PAIN. METHODS OF PREPARATION AND THERAPEUTIC USE MICROBIOLÓGICA QUÍMICA E FARMACÊUTICA LTDA. (BR) 2025-12-26 WO disclosed
WO-2025260159-A1 ISOINDOLINE AND INDOLINE DERIVATIVE COMPOUNDS, COMBINATIONS, PHARMACEUTICAL COMPOSITIONS, MEDICAMENTS, USE OF THE COMPOUNDS AND METHOD OF TREATMENT OF PAIN MICROBIOLÓGICA QUÍMICA E FARMACÊUTICA LTDA. (BR) 2025-12-26 WO disclosed
US-20250302737-A1 POLYMERIC MICRONEEDLE ARRAYS CROSSLINKED BY PBA-DIOL COMPLEXES FOR GLUCOSE-RESPONSIVE INSULIN DELIVERY UNIV NOTRE DAME DU LAC (US) 2025-10-02 US disclosed
US-4318913-A 1,2,4-Triazole-3,5-diamine derivatives GLAXO GROUP LIMITED (GB) 1982-03-09 US disclosed
EP-0045150-A1 Antibacterial compounds, processes for their preparation and composititions containing them BEECHAM GROUP PLC (GB) 1982-02-03 EP disclosed
US-3959351-A INSECTICIDE, CHOLINESTERASE INHIBITOR RESEARCH CORPORATION (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040236146-A1 Method for producing 3-bromomethylbenzoic acids CYP2F1, CYP1B1, BCAT2 FOLH1 1811/4885MEP1B 36/4885MEP1A 93/4885
US-20250302737-A1 POLYMERIC MICRONEEDLE ARRAYS CROSSLINKED BY PBA-DIOL COMPLEXES FOR GLUCOSE-RESPONSIVE INSULIN DELIVERY GPR119, IAPP, INSR FOLH1 2580/4885MEP1B 3436/4885MEP1A 3956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.