SCHEMBL29964040

SCHEMBL29964040

O=C(O)c1cccc(CBr)c1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.66
MEP1B Q16820 3/20 0.58
MEP1A Q16819 1/20 0.58
MRGPRX4 Q96LA9 2/20 0.54
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
HIF1A Q16665 1/20 0.53
ANPEP P15144 1/20 0.53
ENPEP Q07075 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA6 P23280 1/20 0.52
CA9 Q16790 1/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40393 1.00 FOLH1 (0.66) FOLH1MEP1BMEP1AMRGPRX4CYP2D6
SCHEMBL6895867 0.85 GSK3B (0.60) FOLH1MEP1BMEP1AMRGPRX4
SCHEMBL29572523 0.85 ATM (0.52) FOLH1MEP1BMEP1ACES2CES1
SCHEMBL2062793 0.85 CES2 (0.48) FOLH1MEP1BMEP1AMRGPRX4CES2
SCHEMBL185962 0.85 ATM (0.52) FOLH1MEP1BMEP1ACES2CES1
SCHEMBL29728644 0.84 L3MBTL1 (0.63) FOLH1CES2CES1
SCHEMBL1815690 0.84 FOLH1 (0.61) FOLH1MEP1BMEP1AMRGPRX4CYP2D6
SCHEMBL435297 0.84 L3MBTL1 (0.63) FOLH1CES2CES1
SCHEMBL70351 0.83 FOLH1 (0.70) FOLH1MEP1BCYP2D6CYP2C9HIF1A
SCHEMBL371526 0.83 FOLH1 (0.70) FOLH1MEP1BMEP1AMRGPRX4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116716029-B Long-acting antibacterial and antiviral polyester finishing paint and preparation method thereof 中海油常州涂料化工研究院有限公司 2024-04-30 CN claimed
CN-116716029-A Long-acting antibacterial and antiviral polyester finishing paint and preparation method thereof 中海油常州涂料化工研究院有限公司 2023-09-08 CN claimed
CN-112646159-B Preparation method of quaternary ammonium salt modified polyester resin for antibacterial powder coating 浙江光华科技股份有限公司 2022-09-27 CN claimed
US-20250302737-A1 POLYMERIC MICRONEEDLE ARRAYS CROSSLINKED BY PBA-DIOL COMPLEXES FOR GLUCOSE-RESPONSIVE INSULIN DELIVERY UNIV NOTRE DAME DU LAC (US) 2025-10-02 US disclosed
EP-4507715-A1 POLYMERIC MICRONEEDLE ARRAYS CROSSLINKED BY PBA-DIOL COMPLEXES FOR GLUCOSE-RESPONSIVE INSULIN DELIVERY University of Notre Dame du Lac (US) 2025-02-19 EP disclosed
CN-119176789-A Novel amidino-containing iNOS inhibitor with neuroprotection function, and preparation method and application thereof 中国药科大学 2024-12-24 CN disclosed
CN-118146308-A Cyclic peptides for treating gastric cancer and pharmaceutical composition thereof 中国科学院分子细胞科学卓越创新中心 2024-06-07 CN disclosed
CN-116716029-B Long-acting antibacterial and antiviral polyester finishing paint and preparation method thereof 中海油常州涂料化工研究院有限公司 2024-04-30 CN disclosed
CN-117897391-A Method for preparing peptide library or peptide 洛桑联邦政府综合工科学校(EPFL) 2024-04-16 CN disclosed
WO-2024026280-A1 POLYMERIC MICRONEEDLE ARRAYS CROSSLINKED BY PBA-DIOL COMPLEXES FOR GLUCOSE-RESPONSIVE INSULIN DELIVERY UNIVERSITY OF NOTRE DAME DU LAC (US) 2024-02-01 WO disclosed
CN-116716029-A Long-acting antibacterial and antiviral polyester finishing paint and preparation method thereof 中海油常州涂料化工研究院有限公司 2023-09-08 CN disclosed
CN-112646159-B Preparation method of quaternary ammonium salt modified polyester resin for antibacterial powder coating 浙江光华科技股份有限公司 2022-09-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302737-A1 POLYMERIC MICRONEEDLE ARRAYS CROSSLINKED BY PBA-DIOL COMPLEXES FOR GLUCOSE-RESPONSIVE INSULIN DELIVERY GPR119, IAPP, INSR FOLH1 2580/4885MEP1B 3436/4885MEP1A 3956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.