Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070284 | 1.00 | HPGD (0.52) | HPGDMEN1CYP1A2MAPTCYP2C19 | |
| SCHEMBL2294384 | 0.89 | CDC7 (0.53) | HPGDMEN1CYP1A2MAPTCYP2C19 | |
| SCHEMBL27839782 | 0.82 | BIRC5 (0.54) | HPGDMAPTCYP2C19PKMCDC7 | |
| SCHEMBL2295440 | 0.81 | CDC7 (0.56) | CYP2C19PKMCDC7CDK2SLC22A12 | |
| SCHEMBL28650970 | 0.81 | CDC7 (0.47) | HPGDCDC7CDK2SLC22A12PARP1 | |
| SCHEMBL27144742 | 0.81 | CDC7 (0.54) | MEN1MAPTCYP2C19KMT2ACDC7 | |
| SCHEMBL30866643 | 0.81 | CDC7 (0.54) | MEN1MAPTCYP2C19KMT2ACDC7 | |
| SCHEMBL30828406 | 0.80 | CDC7 (0.54) | CYP2C19PKMCDC7CDK2SLC22A12 | |
| SCHEMBL1150333 | 0.80 | CDC7 (0.54) | CYP2C19PKMCDC7CDK2SLC22A12 | |
| SCHEMBL13204200 | 0.78 | MKNK2 (0.52) | CYP1A2MAPTCYP2C19CDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480111-A | Synthesis method of 7-azaindole substituted aryl acetate compound | 江苏理工学院 | 2021-03-12 | — | — | CN | disclosed |