Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294384 | 0.89 | CDC7 (0.53) | CDC7CDK2RAPGEF4L3MBTL1HPGD | |
| SCHEMBL16863761 | 0.87 | RAPGEF4 (0.50) | CDC7CDK2RAPGEF4L3MBTL1ALDH1A1 | |
| SCHEMBL28537449 | 0.82 | L3MBTL1 (0.54) | CDC7CDK2PTK2RAPGEF4L3MBTL1 | |
| SCHEMBL2295440 | 0.81 | CDC7 (0.56) | CDC7CDK2RAPGEF4L3MBTL1SLC22A12 | |
| SCHEMBL28545337 | 0.81 | HPGD (0.52) | CDC7CDK2ALDH1A1HPGDXDH | |
| SCHEMBL31070284 | 0.81 | HPGD (0.52) | CDC7CDK2ALDH1A1HPGDXDH | |
| SCHEMBL27144742 | 0.81 | CDC7 (0.54) | CDC7CDK2RAPGEF4ATMALDH1A1 | |
| SCHEMBL30866643 | 0.81 | CDC7 (0.54) | CDC7CDK2RAPGEF4ATMALDH1A1 | |
| SCHEMBL30828406 | 0.80 | CDC7 (0.54) | CDC7CDK2L3MBTL1ALDH1A1SLC22A12 | |
| SCHEMBL1150333 | 0.80 | CDC7 (0.54) | CDC7CDK2L3MBTL1ALDH1A1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461681-B | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2024-03-15 | — | — | CN | claimed |
| CN-113461681-A | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2021-10-01 | — | — | CN | claimed |
| CN-113461681-B | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-113461681-A | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2021-10-01 | — | — | CN | disclosed |